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Neousys MezIO-C180-50 8-Port Serial MezIO Module with 4x RS-232/422/485 and 4x RS-232

The MezIO-C180-50 is the RS-232 weighted module in the Neousys MezIO-C180/C181 series: an eight-port serial MezIO module with four RS-232/422/485 multi-mode ports and four RS-232 ports on one SCSI-II 68-pin connector. It suits lines and cabinets where older RS-232 instruments and RS-485 devices share one computer.

  • Four RS-232 Ports Plus Four Multi-Mode: Four dedicated RS-232 ports sit alongside four RS-232/422/485 ports, so older RS-232 instruments and newer RS-485 devices share one module.
  • 50 bps to 921.6 Kbps Baud Rates: Every port runs from 50 bps up to 921.6 Kbps, with 256-byte TX and RX FIFOs to buffer traffic at the higher rates.
  • BIOS-Configurable Mode and Termination: Mode and termination on the four multi-mode ports are set in the BIOS, so each can run as RS-232, RS-422 or RS-485.
  • ESD Protection and Full Handshake Lines: Every port has ESD protection, and the RS-232 ports bring out full handshake lines: TxD, RxD, RTS, CTS, DTR, DSR and DCD.
  • One SCSI-II Connector to Eight DB-9: All eight ports leave on one 68-pin SCSI-II female connector, broken out to eight DB-9 male plugs by a 50 cm cable.
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MezIO-C180-50 Overview

Serial is still how a lot of plant equipment talks. Weighing scales, barcode readers, older PLCs and test instruments often offer nothing but an RS-232 port, while drives, meters and newer sensors tend to sit on an RS-485 bus. The MezIO-C180-50 is part of the Neousys MezIO-C180/C181 series of eight-port serial MezIO modules, and it is the version weighted towards RS-232.

It gives the host computer four RS-232/422/485 multi-mode ports and four RS-232 ports, each running from 50 bps to 921.6 Kbps with 256-byte TX and RX FIFOs and ESD protection. Mode and termination on the multi-mode ports are set in the BIOS, so one MezIO-C180-50 can serve an RS-485 drive chain and several RS-232 instruments at the same time. Windows 10 and Linux are supported. Where RS-422/485 matters more than extra RS-232, the MezIO-C181-50 swaps the four RS-232 ports for four RS-422/485 ports.

We fit the MezIO-C180-50 inside the Neousys system on its high-speed board-to-board connector with three-point mezzanine mounting, then set the port modes and test the build before it ships. Each system has one MezIO interface, so the serial module takes that position. It fits the Nuvo-9000, Nuvo-11000, Nuvo-11160GC, Nuvo-9160GC and Nuvo-9166GC series, and the compact POC-900, POC-700, POC-700-FT and POC-600 computers.

All eight ports leave the system on one 68-pin SCSI-II female connector. One connector for all eight ports keeps the serial cabling at the computer to a single run, which makes each device easier to trace in a cabinet. RS-422 ports use TxD+, TxD-, RxD+ and RxD-, and RS-485 ports use Data+ and Data-. If you are not sure which mix of ports your equipment needs, send us the device list and we can check it before we build.

MezIO-C180-50 Specifications

Overview
Brand & ModelNeousys MezIO-C180-50
Performance
Operating SystemLinux
Windows 10
I/O
Serial8x Serial Ports
4x RS232 [SCSI-68]
4x RS232/422/485 [SCSI-68]

MezIO-C180-50 Compatible Systems

MezIO-C180-50 fits the Neousys systems below. We fit and test the module inside the system before it ships. Each card shows the models in that series the module fits.

  • CPU: Intel Core 12th Gen Alder Lake, Intel Core 13th Gen Raptor Lake
  • Memory: 2x DDR5 4800MHz SO-DIMM Slot, 64GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x Display Port, 1x DVI, 1x VGA
  • USB: 1x USB 3.2 Gen 2x2 [Type C], 2x USB 2.0 [Type A], 2x USB 3.2 Gen 1 [Type A], 4x USB 3.2 Gen 2 [Type A]
  • Serial: 2x RS232 [DB9], 2x RS232/422/485 [DB9]
  • M.2: 1x M.2 B-Key [PCIe x1/USB/SIM] [2242/3052], 1x M.2 M-Key [PCIe x4 Gen4] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB]
  • Storage: 1x M.2 SSD [M-Key 2280, PCIe Gen 4 x4], 2x 2.5" HDD/SSD [SATA]
  • RAID: RAID 0, RAID 1
  • Ignition Sensing: Supports Ignition Control
  • Temp: -25°C to 70°C [-13°F to 158°F]
  • Mounting Options: DIN Mount, Wall Mount
  • Ethernet: 1x 2.5 GbE LAN [RJ45], 1x GbE LAN [RJ45]
  • PCIe: 1x PCIe [x16 Slot] [x8 Signal] [Gen3]
  • Power: 8-48V DC [Terminal Block]
  • Certification: CE, FCC
COMPARE VARIANTS
Select Nuvo-9000 Variant
Nuvo-9002DE : NUVO-9000 with dual-slot PCIe Cassette, 2.5GbE plus GbE
Nuvo-9002DE-UL : NUVO-9000 with dual-slot PCIe Cassette, 2.5GbE plus GbE, UL 62368-1
Nuvo-9002E : NUVO-9000 with single-slot PCIe Cassette, 2.5GbE plus GbE
Nuvo-9002E-UL : NUVO-9000 with single-slot PCIe Cassette, 2.5GbE plus GbE, UL 62368-1
Nuvo-9002LP : NUVO-9000 with hot-swap 2.5" drive tray, 2.5GbE plus GbE
Nuvo-9002LP-UL : NUVO-9000 with hot-swap 2.5" drive tray, 2.5GbE plus GbE, UL 62368-1
Nuvo-9002P : NUVO-9000 with single-slot PCI Cassette, 2.5GbE plus GbE
Nuvo-9002P-UL : NUVO-9000 with single-slot PCI Cassette, 2.5GbE plus GbE, UL 62368-1
Nuvo-9006DE : NUVO-9000 with dual-slot PCIe Cassette, 5x 2.5GbE plus GbE, PoE+ option
Nuvo-9006DE-UL : NUVO-9000 with dual-slot PCIe Cassette, 5x 2.5GbE plus GbE, PoE+ option, UL 62368-1
Nuvo-9006E : NUVO-9000 with single-slot PCIe Cassette, 5x 2.5GbE plus GbE, PoE+ option
Nuvo-9006E-UL : NUVO-9000 with single-slot PCIe Cassette, 5x 2.5GbE plus GbE, PoE+ option, UL 62368-1
Nuvo-9006LP : NUVO-9000 with hot-swap 2.5" drive tray, 5x 2.5GbE plus GbE, PoE+ option
Nuvo-9006LP-UL : NUVO-9000 with hot-swap 2.5" drive tray, 5x 2.5GbE plus GbE, PoE+ option, UL 62368-1
Nuvo-9006P : NUVO-9000 with single-slot PCI Cassette, 5x 2.5GbE plus GbE, PoE+ option
Nuvo-9006P-UL : NUVO-9000 with single-slot PCI Cassette, 5x 2.5GbE plus GbE, PoE+ option, UL 62368-1
  • CPU: Intel Pentium G Series Alder Lake, Intel Core 12th Gen Alder Lake, Intel Core 13th Gen Raptor Lake, Intel Celeron G Series Alder Lake
  • GPU / AI Accelerator: Discrete GPU (PCIe)
  • GPU: NVIDIA RTX PRO 2000 Blackwell, NVIDIA RTX PRO 4000 Blackwell SFF, NVIDIA RTX 2000E Ada
  • AI Performance: 142–770 TOPS
  • Memory: 2x DDR5 4800MHz SO-DIMM Slot, 64GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x Display Port, 1x DVI, 1x VGA
  • Ethernet: 1x GbE LAN [RJ45], 5x 2.5 GbE LAN [RJ45]
  • USB: 1x USB 3.2 Gen 2x2 [Type C], 2x USB 2.0 [Type A], 2x USB 3.2 Gen 1 [Type A], 4x USB 3.2 Gen 2 [Type A]
  • Serial: 2x RS232 [DB9], 2x RS232/422/485 [DB9]
  • M.2: 1x M.2 B-Key [PCIe x1/USB/SIM] [3042/3052], 1x M.2 M-Key [PCIe x4 Gen4] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB]
  • PCIe: 1x PCIe [x16 Slot] [x16 Signal] [Gen3]
  • Storage: 1x M.2 SSD [M-Key 2280, PCIe Gen 4 x4], 2x 2.5" HDD/SSD [SATA]
  • RAID: RAID 0, RAID 1
  • Power: 8-48V DC [Terminal Block]
  • Temp: -25°C to 60°C [-13°F to 140°F]
  • Certification: CE, FCC
  • Mounting Options: Wall Mount
  • CPU: Intel Pentium G Series Alder Lake, Intel Core 12th Gen Alder Lake, Intel Core 13th Gen Raptor Lake, Intel Celeron G Series Alder Lake
  • GPU / AI Accelerator: Discrete GPU (PCIe)
  • GPU: NVIDIA L4
  • AI Performance: 485 TOPS
  • Memory: 2x DDR5 4800MHz SO-DIMM Slot, 64GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x Display Port, 1x DVI, 1x VGA
  • Ethernet: 1x GbE LAN [RJ45], 5x 2.5 GbE LAN [RJ45]
  • USB: 1x USB 3.2 Gen 2x2 [Type C], 2x USB 2.0 [Type A], 2x USB 3.2 Gen 1 [Type A], 4x USB 3.2 Gen 2 [Type A]
  • Serial: 2x RS232 [DB9], 2x RS232/422/485 [DB9]
  • M.2: 1x M.2 B-Key [PCIe x1/USB/SIM] [3042/3052], 1x M.2 M-Key [PCIe x4 Gen4] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB]
  • PCIe: 2x PCIe [x16 Slot] [x8 Signal] [Gen3] [Cassette]
  • Storage: 1x M.2 SSD [M-Key 2280, PCIe Gen 4 x4], 2x 2.5" HDD/SSD [SATA]
  • RAID: RAID 0, RAID 1
  • Power: 8-48V DC [Terminal Block]
  • Temp: -25°C to 60°C [-13°F to 140°F]
  • Mounting Options: Wall Mount
  • Certification: CE, FCC
COMPARE VARIANTS
Select Nuvo-9166GC Variant
Nuvo-9166GC : Nuvo-9166GC with NVIDIA L4, second PCIe slot, 8 V to 48 V DC
Nuvo-9166GC-UL : Nuvo-9166GC with NVIDIA L4, dual PCIe slots, 24 V DC input and UL 62368-1
  • CPU: Intel Core Ultra Series 2 Arrow Lake-S
  • GPU / AI Accelerator: Intel NPU
  • AI Performance: 13 TOPS
  • Memory: 2x DDR5 6400MHz SO-DIMM Slot, 64GB
  • OS: Linux, Windows 10, Windows 11
  • Serial: 2x RS232 [DB9], 2x RS232/422/485 [DB9]
  • mPCIe: 2x mPCIe [PCIe/USB]
  • RAID: RAID 0, RAID 1
  • Power: 8-48V DC [Terminal Block]
  • Ignition Sensing: Supports Ignition Control
  • Certification: CE, EN55032, FCC
  • Mounting Options: DIN Mount, Wall Mount
  • Display Outputs: 1x Display Port, 2x HDMI
  • Ethernet: 1x 2.5 GbE LAN [RJ45], 1x GbE LAN [RJ45]
  • USB: 2x USB 3.2 Gen 1 [Type A], 2x USB 3.2 Gen 2 [Type A], 4x USB 2.0 [Type A]
  • PCIe: 1x PCIe [x16 Slot] [1x16 Signal or 2x8 Signal] [Gen4]
  • Storage: 2x 2.5" HDD/SSD [SATA]
  • Temp: -25°C to 70°C [-13°F to 158°F]
COMPARE VARIANTS
Select Nuvo-11000 Variant
Nuvo-11002E : NUVO-11000 with single-slot PCIe Gen4 x16 Cassette, 2.5GbE plus GbE
Nuvo-11002LP : NUVO-11000 with hot-swap 2.5" drive tray, 2.5GbE plus GbE
Nuvo-11006DE : NUVO-11000 with dual-slot PCIe Cassette, 6 LAN ports, PoE+ and 10GbE options
Nuvo-11006E : NUVO-11000 with single-slot PCIe Cassette, 6 LAN ports, PoE+ and 10GbE options
Nuvo-11006LP : NUVO-11000 with hot-swap 2.5" drive tray, 6 LAN ports, PoE+ and 10GbE options
  • CPU: Intel Core Ultra Series 2 Arrow Lake-S
  • GPU / AI Accelerator: Discrete GPU (PCIe)
  • AI Performance: 13 TOPS
  • Memory: 2x DDR5 6400MHz SO-DIMM Slot, 64GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x HDMI, 2x Display Port
  • Ethernet: 1x GbE LAN [RJ45], 5x 2.5 GbE LAN [RJ45]
  • USB: 1x USB 2.0 [Type A], 8x USB 3.2 Gen 2 [Type A]
  • Serial: 2x RS232 [DB9], 2x RS232/422/485 [DB9]
  • M.2: 1x M.2 M-Key [PCIe x4 Gen5] [2280]
  • mPCIe: 2x mPCIe [PCIe/USB]
  • PCIe: 1x PCIe [x16 Slot] [1x16 Signal or 2x8 Signal] [Gen4]
  • Storage: 1x M.2 SSD [PCIe], 2x 2.5" HDD/SSD [SATA]
  • RAID: RAID 0, RAID 1
  • Power: 8-48V DC [Terminal Block]
  • Temp: -25°C to 60°C [-13°F to 140°F]
  • Certification: CE, EN55032, FCC
  • Mounting Options: Wall Mount
  • CPU: Intel Atom X Series Alder Lake
  • Memory: 1x DDR5 4800MHz SO-DIMM, 16GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 2x HDMI
  • USB: 2x USB 3.2 Gen 1 [Type A], 2x USB 3.2 Gen 2 [Type A]
  • Serial: 1x RS422/485 [DB9], 1x RS232/422/485 [DB9], 3x RS232 [DB9]
  • M.2: 1x M.2 M-Key [SATA] [2280]
  • Storage: 1x M.2 SSD [SATA]
  • Power: 8-35V DC [Terminal Block]
  • Temp: -25°C to 70°C [-13°F to 158°F]
  • Certification: CE, FCC
  • Mounting Options: DIN Mount, Wall Mount
  • Ethernet: 1x 2.5 GbE LAN [RJ45], 2x 2.5 GbE LAN [RJ45] [PoE]
COMPARE VARIANTS
Select POC-600 Variant
POC-600 : POC-600 with Intel Atom x7425E, 3x 2.5GbE including 2x PoE+ and DIN-rail mount
POC-610 : POC-600 with Intel Atom x7425E, 3x 2.5GbE without PoE and DIN-rail mount
  • Memory: 1x DDR5 4800MHz SO-DIMM, 16GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x Display Port, 1x HDMI
  • USB: 4x USB 3.2 Gen 2 [Type A]
  • Serial: 1x RS232/422/485 [DB9], 3x RS232 [DB9]
  • M.2: 1x M.2 M-Key [PCIe x1/SATA] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB/SIM]
  • Storage: 1x M.2 SSD [PCIe & SATA]
  • Ignition Sensing: Supports Ignition Control
  • Temp: -25°C to 70°C [-13°F to 158°F]
  • Mounting Options: DIN Mount, Wall Mount
  • CPU: Intel Processor N Series Alder Lake
  • Ethernet: 4x GbE LAN [RJ45] [PoE]
  • Power: 8-35V DC [Terminal Block]
  • Certification: CE, FCC
COMPARE VARIANTS
Select POC-700 Variant
POC-712 : POC-700 with Intel Atom x7425E, 4x GbE and 4x USB 3.2 Gen2
POC-712-UL : POC-700 with Intel Atom x7425E, 4x GbE, UL 62368-1 certified
POC-715 : POC-700 with Intel Core i3-N305, 4x GbE PoE+ and 4x USB 3.2 Gen2
POC-715-UL : POC-700 with Intel Core i3-N305, 4x GbE PoE+, UL 62368-1 certified
  • Memory: 1x DDR5 4800MHz SO-DIMM, 16GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 1x Display Port, 1x HDMI
  • USB: 4x USB 3.2 Gen 2 [Type A]
  • Serial: 1x RS232/422/485 [DB9], 3x RS232 [DB9]
  • M.2: 1x M.2 M-Key [PCIe x1/SATA] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB/SIM]
  • Storage: 1x M.2 SSD [PCIe & SATA]
  • Power: 8-35V DC [Terminal Block]
  • Ignition Sensing: Supports Ignition Control
  • Temp: -25°C to 60°C [-13°F to 140°F]
  • Certification: CE, FCC
  • Mounting Options: Wall Mount
  • CPU: Intel Processor N Series Alder Lake
  • Ethernet: 4x GbE LAN [RJ45] [PoE]
COMPARE VARIANTS
Select POC-700-FT Variant
POC-712-FT : POC-700-FT with Intel Atom x7425E, 4x GbE and flattop heatsink
POC-715-FT : POC-700-FT with Intel Core i3-N305, 4x GbE PoE+ and flattop heatsink
  • CPU: AMD Ryzen PRO 8000 Series
  • GPU / AI Accelerator: AMD Ryzen AI NPU
  • AI Performance: 16 TOPS
  • Memory: 1x DDR5 5600MHz SO-DIMM Slot, 32GB
  • OS: Linux, Windows 10, Windows 11
  • Display Outputs: 2x HDMI
  • Ethernet: 4x GbE LAN [RJ45] [PoE]
  • USB: 4x USB 3.2 Gen 2 [Type A]
  • Serial: 1x RS232/422/485 [DB9], 3x RS232 [DB9]
  • M.2: 1x M.2 M-Key [PCIe x4] [2280]
  • mPCIe: 1x mPCIe [PCIe/USB/SIM]
  • Storage: 1x M.2 SSD [PCIe]
  • Power: 8-35V DC [Terminal Block]
  • Temp: -25°C to 70°C [-13°F to 158°F]
  • Certification: IEC 62368-1, CE, EN55032, FCC, UL 62368-1
  • Mounting Options: DIN Mount, Wall Mount

Official Neousys USA Distributor

Things Embedded is an official Neousys USA distributor, and we fit the MezIO-C180-50 into the Neousys computer you order, set its port modes and test the build before it ships. Where a Nuvo-9000 system needs isolated digital I/O on its MezIO interface instead, the MezIO-D230/D220 isolated DIO modules offer 16 or 32 channels.

The MezIO-C180-50 sits with our Neousys MezIO modules and our data acquisition and I/O range, and suits computers such as the Nuvo-11000 series.

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